Anthelmintic resistance of gastrointestinal cattle nematodes

  • J. De Graef
  • E. Claerebout
  • P. Geldhof


Anthelmintic resistance of parasites in small ruminants, cattle and horses is increasing worldwide as a consequence of the over usage of the currently available products. In Belgium, Cooperia oncophora is the most common cattle nematode in which resistance, especially against macrocyclic lactones, occurs. Once resistance has been diagnosed, a change to another drug with a different mode of action is advised. However, effective anthelmintics will be hardly available in the near future. Therefore, it is important that farmers and veterinarians find a balance between achieving good parasite control and the sustainability of their control strategies. In this way, anthelmintic resistance may be delayed, and the effectiveness of anthelmintic drugs may be prolonged. This requires sensitive detection tools. With a sensitive detection technique, anthelmintic resistance can be diagnosed in a very early stage. Hence, the spread of resistance alleles in the parasite population may be prevented. In this review, different diagnostic assays for the detection of anthelmintic resistance are discussed, an overview is given of the current status of anthelmintic resistance in Belgian cattle, and measures are suggested to avoid or delay the development of anthelmintic resistance.

How to Cite:

De Graef, J., Claerebout, E. & Geldhof, P., (2013) “Anthelmintic resistance of gastrointestinal cattle nematodes”, Vlaams Diergeneeskundig Tijdschrift 82(3), 113-123. doi:

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Published on
27 Jun 2013
Peer Reviewed