Case Report

Scedosporium apiospermum isolated from a skin wound in a dog and in vitro activity of eleven antifungal drugs

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Abstract

Scedosporium apiospermum, an emerging opportunistic fungus, is increasingly implicated with serious invasive mycoses in immunocompromised patients. Rare occurrence and difficulty in identification of this species complicate the management of infection in dogs. In the present report, the characterization of a Scedosporium apiospermum isolate obtained from a dog’s skin wound is described. Identification was obtained through macroscopic and microscopic examination of the cultured isolate and by sequencing the internal transcribed spacer (ITS) gene of the rRNA region. Numerous hyaline septate hyphae along with conidia were observed histologically. The isolate exhibited low MIC values for voriconazole, itraconazole and isavuconazole while high MIC/MEC values were recorded for the remaining antifungals. To the best of the authors’ knowledge, this is the first reported case of isolation of S. apiospermum from a skin wound in a dog.

How to Cite:

Singh, A. & Debnath, C. & Biswas, R. & Barua, R. & Gurung, N., (2022) “Scedosporium apiospermum isolated from a skin wound in a dog and in vitro activity of eleven antifungal drugs”, Vlaams Diergeneeskundig Tijdschrift 91(6), 268–272. doi: https://doi.org/10.21825/vdt.85518