Review

Mucosa-associated lymphoid tissue lymphoma

Authors: , , , , ,

Abstract

In this literature review, an overview of the current knowledge of MALT lymphoma in man is provided. Where appropriate, attention is paid to the presence of the lesion in veterinary medicine. Lymphomas of the mucosa-associated lymphoid tissue (MALT) may originate from lymphoid tissue that is induced in the mucosae. The knowledge of these tumors in veterinary medicine is limited to the relation between gastric MALT lymphoma and infection with Helicobacter species in the cat. The diagnosis is based on the symptomatology, such as vomiting and anorexia, and histology of gastric biopsies. In human medicine, immunohistochemical analysis and in situ hybridization have diagnostic value. Cats can be treated by eliminating the bacterial infection and by surgery. In humans, chemotherapy, radiation therapy and antibody therapy are additional options. The prognosis is favorable in most human cases, but is negatively influenced in the cat by complicating factors, such as infection with the feline leukemia virus.

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How to Cite: Van Hoey, C. , Van den Broeck, W. , Prims, S. , Van Cruchten, S. , Van Ginneken, C. & Casteleyn, C. (2016) “Mucosa-associated lymphoid tissue lymphoma”, Vlaams Diergeneeskundig Tijdschrift. 85(3). doi: https://doi.org/10.21825/vdt.v85i3.16339