Testicular disorder of sex development (78,XX SRY-negative) in a female French bulldog
- A. Van Cleven
- E. Wydooghe
- L. Van Brantegem
- I. Szczerbal
- M. Stachowiak
- M. Switonski
- H. de Rooster
Abstract
A presumably female intact French bulldog of ten months old was presented to the Faculty of Veterinary Medicine of the Ghent University with an enlarged clitoris and purulent vaginal discharge. It was suggested to remove the enlarged clitoris as to avoid further irritation and to perform a gonadectomy at the same time, since the owners were not planning to breed with the dog. An abnormal reproductive tract was observed during surgery. A normal uterus was present, but both gonads resembled testes. Histologic examination of the resected tissues confirmed the presence of bilateral testes in combination with a normal uterus. Karyotyping and molecular analysis of the SRY-gene resulted in a 78,XX SRYnegative karyotype. The French bulldog was diagnosed with a 78,XX SRY-negative testicular disorder of sex development (DSD).
How to Cite:
Van Cleven, A. & Wydooghe, E. & Van Brantegem, L. & Szczerbal, I. & Stachowiak, M. & Switonski, M. & de Rooster, H., (2015) “Testicular disorder of sex development (78,XX SRY-negative) in a female French bulldog”, Vlaams Diergeneeskundig Tijdschrift 84(6), 318-325. doi: https://doi.org/10.21825/vdt.v84i6.16438
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