2A4_0450_ DESIGN OF PATTERNED POLYURETHANE SCAFFOLDS FOR TISSUE ENGINEERING APPLICATIONS
- Neda Shah Hosseini
- N. Bölgen
- N. Khenoussi
- S. Ceylan
- D. Göktürk
- L. Schacher
- Dominique Adolphe
Abstract
The fibrous scaffold production with desired structure plays an important role in multidisciplinary field of tissue engineering. Electrospinning is popular approach for creating nanofibrous substrates in which the filaments resembling the natural extra cellular matrix (ECM) can provide topographical cues to cells directing their growth. One of the major challenges in electrospinning is tailoring the spatial organization of the filaments. To overcome this challenge, a hybrid static collector was utilized that enabled us to form distinct filament organizations on a single substrate. The effect of the filament organization on cellular growth was studied. The engineered scaffolds are promising candidates for fabrication interfaces between various tissues.
Keywords: Electrospinning, spatial nano-filament organization, tissue interfaces, hybrid collectors
How to Cite:
Shah Hosseini, N. & Bölgen, N. & Khenoussi, N. & Ceylan, S. & Göktürk, D. & Schacher, L. & Adolphe, D., (2019) “2A4_0450_ DESIGN OF PATTERNED POLYURETHANE SCAFFOLDS FOR TISSUE ENGINEERING APPLICATIONS”, Proceedings of the 19th World Textile Conference - Autex 2019 , 6.
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