Electrospinning

2B3_0728_ ELECTROSPUN KERATIN/POLY(BUTYLENE SUCCINATE) MATS FOR WOUND HEALING AND DRUG DELIVERY APPLICATIONS

Authors: Annalisa Aluigi , T. Posati , G. Sotgiu , R. Zamboni , G. Guidotti , M. Soccio , A. Munari , N. Lotti , M. Barbalinardo , F. Valle

Abstract

Regenerated wool keratin is a promising natural material for wound dressing. In the present study, keratin extracted from wool was blended with poly(butylene succinate) in 1,1,1,3,3,3-hexafluoro-2-propanol (blending ratio 50/50) and electrospun into nanofibrous mats. Compared to the pure poly(butylene succinate) nanofibres, the keratin based ones showed lower diameters, lower mechanical properties but an increased biodegradability, a delayed diclofenac release and increased bioactivity.

Keywords: wound dressing, drug delivery, keratin, electrospinning

How to Cite: Aluigi, A. , Posati, T. , Sotgiu, G. , Zamboni, R. , Guidotti, G. , Soccio, M. , Munari, A. , Lotti, N. , Barbalinardo, M. & Valle, F. (2019) “2B3_0728_ ELECTROSPUN KERATIN/POLY(BUTYLENE SUCCINATE) MATS FOR WOUND HEALING AND DRUG DELIVERY APPLICATIONS”, Proceedings of the 19th World Textile Conference - Autex 2019.(0).