Electrospinning

2B3_0728_ ELECTROSPUN KERATIN/POLY(BUTYLENE SUCCINATE) MATS FOR WOUND HEALING AND DRUG DELIVERY APPLICATIONS

Authors
  • Annalisa Aluigi
  • T. Posati
  • G. Sotgiu
  • R. Zamboni
  • G. Guidotti
  • M. Soccio
  • A. Munari
  • N. Lotti
  • M. Barbalinardo
  • F. Valle

Abstract

Regenerated wool keratin is a promising natural material for wound dressing. In the present study, keratin extracted from wool was blended with poly(butylene succinate) in 1,1,1,3,3,3-hexafluoro-2-propanol (blending ratio 50/50) and electrospun into nanofibrous mats. Compared to the pure poly(butylene succinate) nanofibres, the keratin based ones showed lower diameters, lower mechanical properties but an increased biodegradability, a delayed diclofenac release and increased bioactivity.

Keywords: wound dressing, drug delivery, keratin, electrospinning

How to Cite:

Aluigi, A., Posati, T., Sotgiu, G., Zamboni, R., Guidotti, G., Soccio, M., Munari, A., Lotti, N., Barbalinardo, M. & Valle, F., (2019) “2B3_0728_ ELECTROSPUN KERATIN/POLY(BUTYLENE SUCCINATE) MATS FOR WOUND HEALING AND DRUG DELIVERY APPLICATIONS”, Proceedings of the 19th World Textile Conference - Autex 2019 , 5.

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Published on
13 Aug 2019
Peer Reviewed